Douglas A. Fein received a B.A. degree (magna cum laude) in history from Brown University in 1983 and received an M.D. degree from Bowman Gray School of Medicine in 1989. Dr. Fein completed his residency in radiation oncology at the University of Florida College of Medicine from 1990-1993 where he was elected chief resident in 1992.

Dr. Fein became an associate member of the Department of Radiation Oncology at the Fox Chase Cancer Center in Philadelphia in 1993 where he was appointed director of the residency training program in 1996. In 1997, he joined Texas Oncology, P.A. as a staff Radiation Oncologist.

Dr. Fein has been a member of the American College of Radiology Committee on Marketing/Public Relations and the National Comprehensive Cancer Network Guideline Committee for Sarcoma since 1996. Since 1999, Dr. Fein has been the director of the Tumor Board at the Medical Center at Princeton.